Toluene Alters p75NTR Expression in the Rat Brainstem
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چکیده
منابع مشابه
Toluene alters p75NTR expression in the rat brainstem.
Toluene is a neurotoxic organic solvent widely used in industry. Acute toluene administration in rats induced a significant increase in the numbers of neural cells immunostained for p75NTR in several brainstem regions, such as the raphe magnus and the nucleus of the solitary tract, as well as in the lateral reticular, gigantocellular, vestibular and ventral cochlear nuclei, without any in the f...
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Acute exposure to high doses of toluene can generate respiratory depression. However, neurotoxic mechanism of its action in the brainstem is not completely clear. In this work, acute, but not subchronic, exposure of rats to toluene increased leu-enkephalin immunostaining in several myelencephalic nuclei implicated in cardiorespiratory control. Due to the physiological role of enkephalins in the...
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ژورنال
عنوان ژورنال: INDUSTRIAL HEALTH
سال: 2004
ISSN: 0019-8366,1880-8026
DOI: 10.2486/indhealth.42.75